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Approved Studies

Protocol Study Status Title
Principal Investigator
CTOTC-01 Closed Immunosuppression Minimization to Single Drug Therapy with Sirolimus (Rapamune®) in Pediatric Transplantation William Harmon, M.D.
CTOTC-02 Closed Immune Development and Alloimmunity in Pediatric Renal Transplant Recipients Allan Kirk, M.D., PhD.
CTOTC-03 Active, Not Recruiting Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation Stuart Sweet, M.D., PhD.
CTOTC-04 Active, Not Recruiting Pediatric Heart Transplantation Across a Positive Donor Specific Cross-Match Steven Webber, M.D., PhD.
CTOTC-05 Closed Perceived Barriers to Patient Adherence after Pediatric Solid Organ Transplantation Stuart Sweet, M.D., PhD.
CTOTC-06 Active, Recruiting Biomarkers for Post-Transplant Lymphoproliferative Disorders in Children Carlos Esquivel, MD, PhD
CTOTC-07 In Development Polyclonal Tregs to Promote Tolerance in Pediatric Liver Transplant Recipients Sandy Feng, MD, PhD
CTOTC-08 Active, Recruiting B Cell Targeted Induction to Improve Outcomes in Pediatric Lung Transplantation Stuart Sweet, MD
CTOTC-09 Active, Recruiting An Observational Cohort Study to Determine the Impact of Donor-Specific HLA Antibodies (Pre-formed versus De Novo) and Antibodies to Self Antigens (Cardiac Myosin, Vimentin) on Chronic Graft Outcomes up to 5 years after Pediatric Heart Transplantation Steven A Webber, MBChB, MRCP
CTOTC-10 In Development Randomized Controlled Trial of Novel Mobile Device Application to Improve Adherence in Children >11 years of age After Cardiac Transplantation Steven A Webber, MBChB, MRCP
CTOTC-11 In Development Prevalence and Correlates of PTSS in Adolescent Solid Organ Transplant Recipients Stuart Sweet, MD, PhD
CTOTC-12 Active, Recruiting Safety of Donor Alloantigen Reactive Tregs to Facilitate Minimization and/or Discontinuation of Immunosuppression in Adult Liver Transplant Recipients Sandy Feng, MD, PhD



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